Tropical soda apple is a familiar weed to ranchers across Florida. A significant amount of effort and
money has been spent over 20 years to control this pest. However, in 2006 Milestone and Forefront were
registered for use in Florida and dramatically improved the process of TSA control. These herbicides
are highly effective on TSA from a foliar application as well as from soil residual activity. Additionally,
ranchers are no longer required the rancher to mow TSA prior to application to improve the consistency of control.
In order to establish new recommendations for TSA control with Milestone and Forefront, research was
conducted to determine the optimum application timing of these herbicides. Research trials were
established in multiple locations from Tallahassee to Labelle, FL. Milestone at 7 fl. oz/A was applied
at each location in the months of April, June, August, October, December, and February. At each
location we observed that TSA control was >95% one month after treatment in all demonstration plots
regardless of when Milestone was applied. TSA treated in April, June, August, October, and December
had high levels (>95%) of both seedling and established TSA control two months after application.
However, previously established TSA plants started to regrow from the rootstock two months after
the February application (Figure 1), but residual seedling control was comparable to other application
dates across the state. Plants that survived the February application timing did not grow as well as
untreated plants, but flowering and fruiting did occur.
Environmental factors often influence herbicide efficacy. Failure to control TSA with Milestone in
February was likely due to frost before or soon after treatment. Milestone is a very slow herbicide
that often requires 4 to 6 weeks to control TSA. Therefore, a frost before application will likely
damage the leaf tissue and inhibit herbicide entry into the plant. A frost soon after application
would damage the leaf and not allow the herbicide to translocate to the rootstock. This is most
likely the reason why the plants treated in February resprouted after application.
Frost, while not uncommon in north and central Florida, does not occur every year in south Florida. Therefore,
Milestone should not be applied when frost is likely to occur. In Florida, it is recommended that Milestone
or Forefront should not be applied from January through March when TSA is the target weed species.

Figure 1. Response of established tropical soda apple to Milestone applied in February near Labelle.
Note the regrowth from the perennial rootstock. This plant continued to grow and produced fruit and
viable seed within six months after treatment.